Authors
Sofiane Achache, Akram Alhussein, Salim Lamri, Manuel François, Frederic Sanchette, Cesar Pulgarin, John Kiwi, Sami Rtimi,
Title
Sputtered Gum metal thin films showing bacterial inactivation and biocompatibility
In
Colloids and Surfaces B: Biointerfaces
Volume
146
Pages
687–691
Publisher
Elsevier
Year
2016
Publisher's URL
http://www.sciencedirect.com/science/article/pii/S0927776516304994?np=y&npKey=f39bd826b2001f6e021e826a7a0977754e21a052ca6d65316f61eb34bc3105c9
Indexed by
Abstract
Super-elastic Titanium based thin films Ti-23Nb-0.7Ta-2Zr-(O) (TNTZ-O) and Ti-24Nb-(N) (TN-N) (at.%) were deposited by direct current magnetron sputtering (DCMS) in different reactive atmospheres. The effects of oxygen doping (TNTZ-O) and/or nitrogen doping (TN-N) on the microstructure, mechanical properties and biocompatibility of the as-deposited coatings were investigated. Nano-indentation measurements show that, in both cases, 1 sccm of reactive gas in the mixture is necessary to reach acceptable values of hardness and Young’s modulus. Mechanical properties are considered in relation to the films compactness, the compressive stress and the changes in the grain size. Data on Bacterial inactivation and biocompatibility are reported in this study. The biocompatibility tests showed that O-containing samples led to higher cells proliferation. Bacterial inactivation was concomitant with the observed pH and surface potential changes under light and in the dark. The increased cell fluidity leading to bacterial lysis was followed during the bacterial inactivation time. The increasing cell wall fluidity was attributed to the damage of the bacterial outer cell which losing its capacity to regulate the ions exchange in and out of the bacteria.
Affiliations
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